Endocrine Abstracts

Background: Larger thyroid volume and nodular thyroid disease were found to be associated with insulin resistance (IR) in patients with type 2 diabetes (T2DM). Similar analyses is lacking in T1DM.Aims: To check the association between thyroid volume and IR using estimated glucose disposal rate (eGDR) in patients T1DM.Materials and methods: We included 99 consecutive patients with T1DM aged 29 (mean, S.D.=6) with diab...

Introduction: Influence of vitamin D status on metabolic control of type 1 diabetes (T1DM) remains controversial. The marker of long-term metabolic control that was not evaluated in this context is tissue accumulation of advanced glycation endproducts (AGEs), measured using skin autofluorescence. Aim of the study was to determine the association between serum 25-hydroxyvitamin D3 (25(OH)D3) concentration and accumulation of AGEs in adults with T1DM.Mater...

Introduction: Type 1 diabetes (T1DM) is often associated with autoimmune thyroid disease (AITD). Common susceptibility genes increase risk for development of both AITD and T1DM. The influence of this comorbidity on the risk of diabetic microangiopathy is unknown.Methods/design: We included 100 consecutive patients with T1DM (55 men, and 45 women) aged 29 (mean, S.D.=6) with diabetes duration 13 (6) years, 35 had diagnosed at least one micr...